• Case Number :
  • Patient Name :
  • Age/Sex :
  • Patient Location :
  • Hospital Name :
  • Physician Name :
  • Date & Time of Accessioning :
  • Date & Time of Reporting :


Ph -Like ALL Panel


Bone Marrow/ Peripheral Blood




Fluorescence in situ hybridization (FISH)

DIAGNOSISDiagnosis based on the markers tested

Positive for ABL1 gene rearrangement & Negative for CRLF2, PDGFRB gene rearrangement.

  • nuc ish (5′ABL1 x1, 3′ABL1x2)(5′ABL1 sep 3′ ABL1x1) - 198 [99%]
  • nuc ish (ABL1×2) - 02 [01%]
  • nuc ish (ABL2×2) - 200 [100%]
  • nuc ish (CRLF2×2) - 200 [100%]
  • nuc ish (JAK2×2) - 200 [100%]
  • nuc ish (EPOR1×2) - 200 [100%]
  • nuc ish (PDGFRA×2) - 200 [100%]
  • nuc ish (PDGFRB×2) - 200 [100%]
  • nuc ish (CSF1R×2) - 200 [100%]

INTERPRETATIONPositive or negative results of all the markers tested

  • -Probable Positive for ABL1 gene rearrangement on chromosome 9, band q34 in 99% of cells. All the cells show an atypical signal pattern of 1F1R suggestive of deletion of 5 prime of ABL1 gene.
  • - negative for ABL2 gene rearrangement on chromosome 1, band q25.
  • - negative for CRLF2 gene rearrangement on chromosomes X, Y band p 22.3 & p 11.2 respectively.
  • - negative for JAK2 gene rearrangement on chromosome 9, band q24.1.
  • - negative for EPOR gene rearrangement on chromosome 19, band P13.
  • - negative for PDGFRA gene rearrangement on chromosome 4, band q12.
  • - negative for PDGFRB gene rearrangement on chromosome 5, band q32.
  • - negative for CSF1R gene rearrangement on chromosome 5, band q32.

COMMENTS Information regarding the probes used in the test

PROBES USED: ABL1, ABL2, CRLF2, JAK2, PDGFRA, PDGFRB & CSF1R - dual color break apart.
ABL1 telomeric side - spectrum orange
ABL1 centromeric side - green spectrum

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  1. The tests are carried out in the lab with the presumption that the specimen belongs to the patient named or identified in the bill/test request form.
  2. The test results relate specifically to the sample received in the lab and are presumed to have been generated and transported per specific instructions given by the physicians/laboratory.
  3. The reported results are for information and are subject to confirmation and interpretation by the referring doctor.
  4. Some tests are referred to other laboratories to provide a wider test menu to the customer.
  5. CORE Diagnostics Pvt. Ltd. shall in no event be liable for accidental damage, loss, or destruction of specimen,which is not attributable to any direct and mala fide act or omission of CORE Diagnostics Pvt. Ltd. or its employees. Liability of CORE Diagnostics Pvt. Ltd. for deficiency of services, or other errors and omissions shall be limited to fee paid by the patient for the relevant laboratory services.

This report is the property of CORE Diagnostics. The information contained in this report is strictly confidential and is only for the use of those authorized. If you have received this report by mistake, please contact CORE Diagnostics.

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